Scientists have created ''pens'' to edit genes
Controversial CRISPR genre editing technology continues to evolve. Harvard scientists and the Massachusetts Institute of Technology have created some sort of "clues" to edit genes, according to CNET. The purpose of the new tools is to use it for deleting and correcting genetic diseases and mutations.
Scientists' technology is based on CRISPR, but quite modified. They have named it Adenine Base Editor (ABE), and it works with a newly developed enzyme. All this allows technology to work in slightly different ways than CRISPR.
CRISPR is often described as a "scissors" that allows precise DNA cuts and their addition to the genome. ABE's creators describe their method as a "pencil" that rewrites and edits DNA in meaningful "sentences." Molecules in DNA are actually described by letters and are ordered. When it is mixed, mutations and genetic diseases are produced.
ABE addresses the most common genetic mutations in order to correct them. A molecular machine can correct mutations in the living cell genome. Scientists believe the new method is much more efficient and more accurate. If ABE is proven in practice, it can be used to treat thousands of different diseases.
Another new tool for editing genes is RNA Editing for Programmable A to I Replacement or REPAIR. A long and complex name can be explained more easily. It is a tool that corrects and corrects RNA - the relationship between DNA and other cell parts. Changes in RNA are transient while DNA changes are permanent.
This method can also correct genetic mutations and reverse the process of their creation. Therefore, it is also described by scientists as a "pencil" rather than a "scissors" like CRISPR. REPAIR does not touch the genome, but it can still help repair mutations.
Both methods have passed initial tests in a laboratory. They are also used on human cells, but there is still a lot of work to do before they are actually applied to humans.
source https://www.vesti.bg