It is hard to give advice here but it you mention girlfriends and bosses coming and going, people's expectations and family abandonment. None of that is you, it is all outside of you. They are not the cause of your depression but, they may be a catalyst. Spend some time understanding yourself without worrying about what others think, really understanding. Stay away from motivation and psychology and instead listen or read something like Awareness by Anthony De Mello. Listen and think, repeat and listen and think and see where it all leads.

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