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Well, as I said. It's a pretty complex topic so I'll try to answer your question as good as possible with links related to current research.
While caffeine is generally metabolized by a one specific Enzyme of this CYP P450 family (CYP 1A2 to be exact), Naringin mostly inhibits CYP3A4, which belongs to the same Enzyme-system but is part of another subfamily. Thus the effect of your coffee should probably not be significantly increased.
I just searched for some studies who were looking into this and found this.
Feel free to take a look into it.
General description of caffein including the metabolizing enzyme
Studies researching a possible interaction 1 + 2
Studies about the pharmakokinetics of grapefruit juice including some drugs it might interact with (This is not a complete list.) 1 + 2
Don't think every other medicine is save to combine with grapefruit juice. The best thing to drink when you're taking medicine still is simple water.
All in all I doesn't seem like combining grapefruit juice with coffee seems to have a significant impact on the caffein in your blood.
It's like the extra robots are chasing some of your IT-specialists that are mainly experts for one OS but leaving the other ones who are responsible for the "caffeine"-bots' OS do their work in peace.
Haha haven't seen that yet.
Hope you still enjoyed the read and maybe even learned something new (even though I guess you're probably learning this in biochemistry during your medicine studies)
Congratulations! This post has been upvoted from the communal account, @minnowsupport, by Vandaze from the Minnow Support Project. It's a witness project run by aggroed, ausbitbank, teamsteem, theprophet0, and someguy123. The goal is to help Steemit grow by supporting Minnows and creating a social network. Please find us in the Peace, Abundance, and Liberty Network (PALnet) Discord Channel. It's a completely public and open space to all members of the Steemit community who voluntarily choose to be there.
If you like what we're doing please upvote this comment so we can continue to build the community account that's supporting all members.
Amazing article. You really put much effort in it and it is extremely good. Good work buddy! Cheers!
Thanks! I still don't feel like even scratching the surface... But I'm glad you liked it :)
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This is the same reason why drinking Grapefruit juice with coffee can increase the effects of caffeine, right? It slows down the liver processing it.
Well, as I said. It's a pretty complex topic so I'll try to answer your question as good as possible with links related to current research.
While caffeine is generally metabolized by a one specific Enzyme of this CYP P450 family (CYP 1A2 to be exact), Naringin mostly inhibits CYP3A4, which belongs to the same Enzyme-system but is part of another subfamily. Thus the effect of your coffee should probably not be significantly increased.
I just searched for some studies who were looking into this and found this.
Feel free to take a look into it.
General description of caffein including the metabolizing enzyme
Studies researching a possible interaction 1 + 2
Studies about the pharmakokinetics of grapefruit juice including some drugs it might interact with (This is not a complete list.) 1 + 2
Don't think every other medicine is save to combine with grapefruit juice. The best thing to drink when you're taking medicine still is simple water.
All in all I doesn't seem like combining grapefruit juice with coffee seems to have a significant impact on the caffein in your blood.
It's like the extra robots are chasing some of your IT-specialists that are mainly experts for one OS but leaving the other ones who are responsible for the "caffeine"-bots' OS do their work in peace.
Nice read! Upvoted!
I have posted similar topic but in short !
https://steemit.com/health/@himal/daily-health-tips-5-why-you-should-not-take-fruits-during-anti-allergic-medication
Haha haven't seen that yet.
Hope you still enjoyed the read and maybe even learned something new (even though I guess you're probably learning this in biochemistry during your medicine studies)
Thanks for the feedback! :)
you are welcome!
you may read it if you like! thanks
This post was upvoted by 15% from Operation Support sponsored with Whaleshares and BeyondBit !
