RE: The reasons behind the "Hollywood fatigue", and record low Box-office
I believe it is a combination of entertainment elsewhere and the attack on Trump supporters.
I love comedy. Comedy nowadays is terrible. One of the funniest movies of all time "Blazing Saddles" would never be able to exist today due to it being called racist. Hollywood would never fathom creating any movie even close to that today. I believe this is why memes and social media is so popular today because they are filling the comedy void Hollywood created. I've never laughed so hard in recent memory over a picture and some words seen online on social media in the form of a meme.
Also just look at the NFL and compare their losses last season to Hollywoods box office earnings. You insult the American people you pay for it where it hurts the most: in your pockets!