Corona Virus : Vaccine candidates, possible treatments, testing kits and companies
As the novel coronavirus continues to spread across the globe, many are hoping for a cure.
Many companies are working on a vaccine, while other or the same companies are awaiting the testing on a larger scale of drug combinations like hydroxychloroquine, azithromycin, lopinavir/ritonavir and others.
We present you a large list of this vaccines and possible treatments, along the companies that produce them, with sources included.
1. World Health Organization Vaccine/Drug Candidates :
Source :
The list contains information about 44 candidates, from which 41 are in Pre-Clinical testing and three of them are in Phase 1 testing. We know the list shows only two vaccines in Phase 1 testings, but recently University of Oxford moved with it's ChAdOx1 vaccine in Phase 1. This vaccine is funded by the United Kingdom Government.
The other two vaccines that are currently in Phase 1 are Moderna Therapeutics mRNA-1273 and Cansino Biologic's Ad5-nCoV
Gilead's Science Redemsivir seems to be the highest hope for now.
https://www.gilead.com/purpose/advancing-global-health/covid-19
2. Other Vaccine/Drug Candidates that are not on the World Health Organization list :
Apeiron Biologics (Austria, APN01 drug trials in China). Are working with Angalpharma CO LTD (Suzhou,China) with the support of dMED Pharmaceuticals CO (China)
Nano Viricides Inc
Onconova Therapeutics (Rigorsetib drug Phase 3 trial)
Athersys Inc
Bellerophon Therapeutics Inc (FDA approval for emergency expanded access for INOpulse)
Mesoblast Limited : https://finance.yahoo.com/quote/meso?ltr=1
Immunemed Inc
http://www.koreabiomed.com/news/articleView.html?idxno=7596
I-Mab Biopharma
Airway Therapeutics
Tiziana Life Sciences
Beyondspring INC
Algernon Pharmaceuticals Inc
Innovation Pharmaceuticals Inc
https://www.clinicaltrialsarena.com/analysis/coronavirus-mers-cov-drugs/
3. Hydroxychloroquine and Chloroquine
Hydroxychloroquine is one of the most talked about drug recently. There are numerous reports from different countries that this drug can possible be helpful combating the corona virus. Some countries are already using it in combination with azythromycin or lopinavir/ritonavir. Some reports about it being successful came prior to US president Donald Trump mentioning it.
https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-2-69
https://www.ncbi.nlm.nih.gov/pubmed/32205204
https://abcnews.go.com/Health/chloroquine-malaria-drug-treat-coronavirus-doctors/story?id=69664561
Companies :
SANOFI (plaquenil) : https://finance.yahoo.com/quote/SNY/
ORION PHARMA : https://finance.yahoo.com/quote/ORNBV.HE/
TEVA PHARMACEUTICALS INDUSTRIES : https://finance.yahoo.com/quote/TEVA/
MYLAN N.V. : https://finance.yahoo.com/quote/MYL/
COVIS PHARMA (plaquenil)
IPCA LABORATORIES (large quantities of chloroquine, India) : https://finance.yahoo.com/quote/IPCALAB.NS?p=IPCALAB.NS&.tsrc=fin-srch
TAJ PHARMA (India)
Shanghai Zhongxisanwei
Shenshua Pharm
Wuhan Wuyao Pharmaceutical
Elyson Pharmaceutical CO LTD
PMG PHARM CO LTD
Kyung Poong Pharma
Shin Poong Pharmaceutical
Adamed Pharma (Poland)
Advanz Pharma (former Concordia Healthcare)
4. Azythromycin
Companies :
ALMIRALL : https://finance.yahoo.com/quote/ALM.MC?ltr=1
TEVA PHARMACEUTICALS INDUSTRIES : https://finance.yahoo.com/quote/TEVA/
PFIZER INC. (holds majority of patents) : https://finance.yahoo.com/quote/PFE/
INSITE VISION INC (holds some patents)
5. Lopinavir/ritonavir
Companies :
ABBVIE INC (holds all the patents for lopinavir/ritonavir) : https://finance.yahoo.com/quote/ABBV/
https://www.drugbank.ca/drugs/DB01601
https://www.drugbank.ca/drugs/DB00503
ABBOTT LABORATORIES (Kaletra/Aluvia) : https://finance.yahoo.com/quote/ABT/
MYLAN M.V. (generic version of Abbott's Kaletra. Exclusive U.S. rights) : https://finance.yahoo.com/quote/MYL/
http://newsroom.mylan.com/press-releases?item=122988
https://seekingalpha.com/news/3555159-mylan-waives-exclusive-u-s-rights-to-generic-kaletra-shares-down-4
CARDINAL HEALTH INC : https://finance.yahoo.com/quote/CAH/
THE GLORY MEDICINA
ZUELLIG PHARMA
EMCURE PHARMACEUTICALS (EMLETRA)
MATRIX LABORATORIES (SUBSIDIARY OF MYLAN)
Cipla (Lopimune)
Aurobindo
Ranbaxy (V-Letra)
Alkem Laboratories (Ritomax-L)
6. Camostat Mesylate + Amodiaquine (ACE2, TMPSS2 block receptor)
Camostat Mesylate Companies :
Ono Pharm. CO (Originator FOIPAN) : https://finance.yahoo.com/quote/OPHLY/
Sigma-Aldrich (Owned by Merck KGaA) : https://finance.yahoo.com/quote/MRK.DE/
TCI CHEMICAL
NOVARTIS : https://finance.yahoo.com/quote/nvs?ltr=1
Fuji Chemical Industry CO
SUMITOMO CHEMICAL COMP (owned by SUMITOMO)
Amodiaquine Companies :
PFIZER INC. : https://finance.yahoo.com/quote/PFE/
IPCA LABORATORIES (India) : https://finance.yahoo.com/quote/IPCALAB.NS?p=IPCALAB.NS&.tsrc=fin-srch
Korea United Pharm (Korea)
7. Alvesco (ciclesonide)
https://pj.jiho.jp/article/241752
Companies :
Teijin Pharma (Japan)
Covis Pharma (holds patents)
Sunovion Pharmaceuticals
8. Sarilumab-Kevzara
Companies :
Sanofi (rights outside US) : https://finance.yahoo.com/quote/SAN.PA?p=SAN.PA&.tsrc=fin-srch
Regeneron Pharmaceuticals (rights in US) : https://finance.yahoo.com/quote/REGN?p=REGN&.tsrc=fin-srch
9. Ampligen
Companies :
AIM Immunotech INC : https://finance.yahoo.com/quote/AIM/
Natus Laboratories Farmaceuticos
10. Quercetin (zinc ionophor)
https://www.globalresearch.ca/made-canada-solution-coronavirus-outbreak/5708918
Companies :
Quercegen Pharmaceuticals LLC , affiliate of Quercengen Agronegocios (largest producer of Quercetin)
11. Shuanghuanglian
Companies :
Harbin Pharmaceutical Group CO LTD (SHA : 600664) : https://www.bloomberg.com/quote/600664:CH
12. Arbidol
Companies :
Jiangsu Wuzhong Industrial CO LTD (SHA : 600200)
SPC Pharmaceutical Group LTD (HKG : 1093)
Ningbo Menonovo Pharmaceutical CO LTD (SHA : 603538) working together with Simcere Pharmaceutical Group (NYSE : SCR)
13. Daranuvir
https://clinicaltrials.gov/ct2/show/NCT04252274
Companies :
Gilead Sciences : https://finance.yahoo.com/quote/GILD/
Janssen INC's core supplier Chongqing (ties with Gilead Sciences)
Shandong Realcan Pharmaceutical CO (SHE : 000756) - partnership with manufacturers
GD Searle LLC (some patents)
Janssen Sciences Ireland UC (some patents)
14. Australian Lab recreates virus + protein
Biotron Limited (BIT.AX) - ASX
15. Favipiravir (praised by China recently, also saying it has high degree of safety)
Companies :
Fujifilm Toyama Chemicals (brand name Avigan)
Zhejiang Hisun Pharmaceutical (chinese approval for manufacturing)
South Korea says it will not use it do to potential side effects. So we have contradictory statements from China and South Korea.
16. Convalescent Plasma :
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30141-9/fulltext
Companies :
Vir Biotechnology in collaboration with Wuxi Biologics and Biogen :
https://finance.yahoo.com/quote/VIR/
Takeda Pharmaceutical Company Limited (brand name TAK-888) : https://finance.yahoo.com/quote/TAK?p=TAK&.tsrc=fin-srch
Regeneron Pharmaceuticals : https://finance.yahoo.com/quote/REGN?p=REGN&.tsrc=fin-srch
Harbour Biomed
17. Test kits, masks, suits and ventilators :
Test kits :
Abbott Laboratories (US) 5 minute test : https://finance.yahoo.com/quote/ABT/
Aytu Bioscience : https://finance.yahoo.com/quote/AYTU?p=AYTU&.tsrc=fin-srch
Roche Holdings AG : https://finance.yahoo.com/quote/RHHBY?p=RHHBY&.tsrc=fin-srch
Thermo Fisher Scientific Inc : https://finance.yahoo.com/quote/TMO?p=TMO&.tsrc=fin-srch
Seegene Inc : https://finance.yahoo.com/quote/096530.KQ?p=096530.KQ&.tsrc=fin-srch
Sugentech Inc. : https://finance.yahoo.com/quote/253840.KQ?p=253840.KQ&.tsrc=fin-srch
Kurabo Industries Ltd. : https://finance.yahoo.com/quote/3106.T?p=3106.T&.tsrc=fin-srch
Academia Sinica (Taiwan 15 minute immune antibodies test)
TIB (Germany)
Bioresponse
Veredus Laboratories Pte LTD (Singapore)
Novacyt : https://finance.yahoo.com/quote/ALNOV.PA?p=ALNOV.PA&.tsrc=fin-srch
Biomedomics
University of Washington
Alfred Health
BGE Genomics CO LTD (SHE : 300676)
Jiangsu Bioperfectus Technologies (SHA : 688399)
Beijing Hotgen Biotech CO LTD (SHA : 688068)
Masks,suits, ventilators (some produce only one in this category, some produce all of them, some only two. There is no particular order in this category) :
Ford Motor Company : https://finance.yahoo.com/quote/F/
General Motors Company : https://finance.yahoo.com/quote/GM/
3M : https://finance.yahoo.com/quote/MMM/
GE Healthcare
Alpha Pro Tech : https://finance.yahoo.com/quote/APT?p=APT&.tsrc=fin-srch
Lakeland Industries : https://finance.yahoo.com/quote/LAKE?p=LAKE&.tsrc=fin-srch
Toughbuilt Industries : https://finance.yahoo.com/quote/TBLT/
https://globalnews.ca/news/6744049/trump-gm-ventilators-production/
We kept this category small, but there are many other producers of masks, suits or/and ventilators
You can do your own searches for drugs and patents at :
https://www.drugbank.ca/
https://drugs-about.com/
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I know that ModeRNA is already testing their vaccines on humans.
Yes, it seems it more had started to do so. https://www.nytimes.com/2020/04/08/health/coronavirus-vaccines.html
Usually until we have an official vaccine it will take years, but because of the situation it may take less.
keeping in mind that a successful vaccine requires an accurate testing/incubation system in order to first grow and then allow the virus to die in order to develop the correct protein base for the vaccine, I would be leary of early testing from any lab. Just me being thoughtful, sort of..
It's good that you are thoughtful, most people think a vaccine can come anytime. It will some time, maybe not 1-2 years like usually because of the nature of the situation that may speed things up.
@bulls.bears, I actually heard someone in hhs (damned if I can remember his name) say that "with everything working right, it will still be over a year," I guess this is why prez drumpf wanted to purchase that German research lab that already has a leg up on the world with a viable vaccine???
Yes, there was a scandal, don't know if true or not, sources said exactly what you are saying. The company involved is CureVac. I think it's a subsidiary of Moderna and it's a private company.
The whole pandemic is a scam, nothing more than the flu, but there is an agenda here, as it was used in place of a financial crash that was coming anyway, and of course they want those toxic mandated vaccines to cull the global population all part of the UN sustainable goals
i couldn’t agree more!
OK boomer. You are the reason why Trump got elected!