The quote says it all.

Life without friends is like a garden without flowers.

Sadly for many life without friends is a reality these days. Just like the relatively new phenomenon of enormous stretches of farmland that doesn't have a single flower.
It's unnatural for only one crop to use up such enormous stretches of land and also it is unnatural for a human being to be alone for too long, interaction with others is of utmost importance and this too counts for both examples.