Another danger of extra terrestrial travel

Apparently there is also cardio vascular disease to be added on top of radiation caused damage, muscle and bone deterioration, renal problems, etc..

Imagine in what shape astronauts would reach Mars:
http://arstechnica.com/science/2016/07/apollo-astronauts-dying-of-heart-disease-at-4-5x-the-rate-of-counterparts/?comments=1