Sort:  

Hence I think this study is a big leap. If we understand how they pick up genes we can stop the spread of resistance. Well maybe we can't do anything about selecting bacteria that are naturally resistant. But we can stop the spread of resistant genes.

At some point, they do become intrinsic resistance. So, I do agree it is potential breakthrough.

A perfect example is Pseudomonas aeruginosa. These days, we just accept the fact that they have intrinsic resistance to ertapenem. Ten or fifteen years ago, not so much.